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Objective@#To investigate the effect of clinical psychological nursing intervention on negative emotion and quality of life in patients with palliative treatment of digestive tract malignancies.@*Methods@#From June 2016 to June 2018, 100 patients with palliative treatment of digestive tract malignancies admitted to the first people′s hospital of Tianmen city as subjects. According to the random number table, patients were divided into control group and observation group, with 50 in each group. The control group received routine nursing intervention and the observation group received clinical psychological nursing intervention.The Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and Quality of Life Measurement Scale (EORTC QLQ-C30) were used to assess the mental state and quality of life of patients, and the differences of the above indicators before and after intervention were compared.@*Results@#After intervention, the HAMD score and HAMA scores in the observation group were (11.22±1.97) and (8.31±1.77), those scores in the control group were (14.58±2.16) and (9.35±2.49), the difference was statistically significant (t=8.008, 2.367, all P<0.05). After the intervention, the scores of role function, emotional function, fatigue, pain, appetite loss and overall quality of life in the observation group were (68.74±25.93), (72.41±21.70), (47.28±15.66), (30.08±12.10), (26.70±9.13) and (76.85±19.66); however, the socres mentioned above were (57.42±26.35), (62.16±21.52), (56.44±14.90), (37.25±15.18), (30.44±9.30), (67.93±20.75) in the control group. The scores role function, emotional function and overall quality of life were significantly increased in the observation group compared to the control group, while fatigue, pain and appetite loss scores were significantly decreased in the observation group compared to the control group (t=1.999-2.950, all P<0.05).@*Conclusions@#Patients with palliative treatment of digestive tract malignant tumors have obvious negative emotions. Clinical psychological nursing intervention can effectively alleviate negative emotions and improve quality of life. It can be used as an auxiliary method during palliative treatment of malignant tumors of digestive tract.
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Objective To investigate the effect of clinical psychological nursing intervention on negative emotion and quality of life in patients with palliative treatment of digestive tract malignancies. Methods From June 2016 to June 2018 , 100 patients with palliative treatment of digestive tract malignancies admitted to the first people′s hospital of Tianmen city as subjects. According to the random number table, patients were divided into control group and observation group, with 50 in each group. The control group received routine nursing intervention and the observation group received clinical psychological nursing intervention.The Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and Quality of Life Measurement Scale (EORTC QLQ-C30) were used to assess the mental state and quality of life of patients, and the differences of the above indicators before and after intervention were compared. Results After intervention, the HAMD score and HAMA scores in the observation group were (11.22±1.97) and (8.31±1.77), those scores in the control group were (14.58±2.16) and (9.35±2.49), the difference was statistically significant (t=8.008, 2.367, all P<0.05). After the intervention, the scores of role function, emotional function, fatigue, pain, appetite loss and overall quality of life in the observation group were (68.74±25.93), (72.41±21.70), (47.28±15.66), (30.08±12.10), (26.70±9.13) and (76.85±19.66);however, the socres mentioned above were (57.42±26.35), (62.16±21.52), (56.44±14.90), (37.25±15.18), (30.44±9.30), (67.93±20.75) in the control group. The scores role function, emotional function and overall quality of life were significantly increased in the observation group compared to the control group, while fatigue, pain and appetite loss scores were significantly decreased in the observation group compared to the control group (t=1.999-2.950, all P＜0.05). Conclusions Patients with palliative treatment of digestive tract malignant tumors have obvious negative emotions. Clinical psychological nursing intervention can effectively alleviate negative emotions and improve quality of life. It can be used as an auxiliary method during palliative treatment of malignant tumors of digestive tract.
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To investigate the surgical approach and outcomes, as well as prognostic factors for pulmonary metastasectomy. Clinical data of 201 patients treated by pulmonary metastasectomy between January 1990 and December 2009 were retrospectively reviewed. One hundred thirty three patients were received an approach of thoracotomy while 68 with video-assisted thoracoscopic surgery [VATS]. There were 54 lobectomies, 139 wedge resections and 8 pneumonectomies. Hilar or mediastinal lymph nodes dissection or sampling was carried out in 38 patients with lobectomy. The Kaplan-Meier method was used for the survival analysis. Cox proportional hazards model was used for multivariate analysis. The 5 years survival rate of patients after metastasectomy was 50.5%, and the median survival time was 65.9 months. The median survival time of patients with hilar or mediastinal lymph nodes metastasis was 23 months. By univariate analysis, significant prognostic factors included disease-free interval [DFI], number of metastases, number of affected lobe, surgical approach [open vs. VATS] and pathology types. DFI, number of metastases, and pathology types were revealed by Cox multivariate analysis as independent prognostic factors. Surgical resection of pulmonary metastases is safe and effective. Palpation of the lung is still seen as necessary to detect the occult nodule. More accurate and sensitive pre-operative mediastinal staging are required
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Humans , Female , Male , Neoplasm Metastasis , Prognosis , Thoracotomy , Lung Neoplasms/surgery , Thoracic Surgery, Video-Assisted , Treatment OutcomeABSTRACT
Objective To assess the safety and efficacy of an olive oil-based lipid emulsion for parenteral nutrition in patients after esophagectomy.Methods In the randomized controlled trial,60 patients undergoing esophagectomy were divided into study group(n=30,received olive oil-based lipid emulsion)and control group [n=30,received medium-chain triglyceride/long-chain triglyceride(MCT/LCT)emulsion].The parenteral nutrition Was provided for 7-10 postoperative days.The nutritional formulas were equivalent in nitrogen,calorie,osmotic pressure,and fluid volume.Peripheral venous blood tests were performed before operation and on the first and eighth postoperative days.All the patients were evaluated by nutritional status(weight,body mass index,nutritional risk screening,etc.),safety profiles[full blood test,electrolytes,aspartate aminotransferase(AST),alanine amiotransferase(ALT),total bilirubin and direct bilirubin,blood urea nitrogen(BUN),creatinine,blood glucose,etc.],and efficacy indicators(hemoglobin,albumin,total protein,etc.).Results The albumin and total protein levels returned to the normal ranges in beth groups 8 days after operation,although both levels were significantly higher in study group(P=0.000).Also,the difference of total protein levels between the eighth and first postoperative days Was significantly higher in the study group(P=0.002).In addition,the AST and BUN readings returned to normal ranges 8 days after operation in the study group, which were significantly lower than those in control group (P = 0.025, P = 0.013).No serious adverse events were reported in both groups.Other nutritional parameters, renal and hepatic safety profiels, vital signs, and hematology showed no significant difference between two groups.Conclusions Olive oil-based lipid emulsion is a safe and efficient lipid emulsion for parenteral nutrition in patients undergoing esophagectomy.Compared with MCT/LCT, it has less effect on AST and BUN.